Carbohydrates
Report on the Effect of Phaseolaminä
Diet Hope for Carbohydrate Addicts
By Dallas Clouatre, Ph.D.
Are carbohydrates the dieter's worst enemy? This is the current hot and controversial topic in the field of weight loss. On the one hand, most mainstream academic and government diet "experts" maintain that the path to slimness is lined with low fat/high complex carbohydrate foods. On the other hand, many recent best selling books contend that the standard nutritionist's prescription for good health in reality is a recipe for obesity, heart disease and diabetes.
These authors may have a point. Over the last two decades, carbohydrates have come to account for an ever-greater proportion of all calories in the industrial world's diet. According to the high-carbohydrate wisdom, we should all be getting thinner, right?
Yet for more than one out of every three of us -- totaling 60 or 70 million adults in America alone -- putting on weight as we age is the rule, not the exception. What is worse, the proportion of us who are 20% or more above our ideal weight has gone up by more than 30% over the last 10 years. No wonder so many people have been giving up on getting healthy.
To many of us it seems that the war against fat already has been lost. Is there a ray of hope for dieters who are more interested in results than in theories?
The answer is yes.
A number of products have come onto the market, which can help to control the downside of high carbohydrate diets. One of the most interesting is the 'new and improved' starch blocker. Starch blockers first appeared in the early 1980's, but at that time the technology was not adequate to produce a properly concentrated and purified product. This has now changed. It is now possible to purchase a consistently effective starch blocker, which lives up to the original billing.
As dieters who have tried the various low-carbohydrate diets can attest, this opens up a world of possibilities. Low-carbohydrate diets almost always are boring, outrageously restrictive in terms of food choices, hard to manage and just plain difficult to adhere to. Does anyone really want to count protein, fat and carbohydrate grams for life or never be able to share a meal with friends and co-workers? Of course not!
The new starch blocker eliminates the usual downside of low-carbohydrate diets because it is designed to change how the body absorbs carbohydrate calories even though the dieter is eating normally.
Knowing the Enemy – Insulin
Changing carbohydrate absorption is important to the dieter. Although our genes may largely determine who among us can become overweight, it is really our exercise and eating habits, which determine who actually does become overweight. Moreover, it is seldom true that merely overeating is responsible for excess weight. When we look closely, we usually find that those who have gained weight are not guilty of eating more calories, but of burning fewer. The culprit is often a reduced resting metabolism, which causes the weight gainer to put on fat even while eating the same, or fewer calories than lean individuals consume.
The resting metabolism (also called the resting metabolic rate or RMR) is the rate at which the body burns calories when we are not exercising. The resting metabolism accounts for about 70% of all the calories which we burn each day. Increased exercise can help to speed up the resting metabolism for a period of time, so moderate exercise for 20 to 30 minutes once or twice per day can help to burn calories. But the lack of exercise alone is usually not the cause of a sluggish RMR. Some people can greatly increase their daily quota of exercise and still not lose weight. This means that there must be at least one other source of the reduced metabolism experienced by most individuals who have weight problems, and that source is the diet.
The diet consists of both macro-nutrients and micro-nutrients. The first includes proteins, carbohydrates and fats. The second includes vitamins and minerals. Both components of the diet influence weight gain, primarily because both can influence the body's ability to use the hormone insulin. It is the body's secretion of and reaction to insulin which largely controls how much fat we store and how much fat we bum. Diets and nutrients which reduce the amount of insulin required by the body reduce excess weight.
One solution to weight gain, then, is to stop eating those foods which cause insulin to be a problem. Refined carbohydrates in all forms, including both sugars and highly processed foods, upset the body's ability to handle insulin. The scientific name for this is insulin resistance.
Insulin resistance causes the body to make more fats itself, to readily store any fats which are eaten, and to turn off the ability to burn fat for fuel. When you consider the fact that most of the carbohydrates found in the modern industrial world's diet are simple, refined, overcooked and/or over-processed, it is easy to guess one of the primary sources of weight problems in modern nations.
How Does the Starch Blocker Help?
The concept of blocking starch digestion to encourage weight loss was first developed by scientists who noticed that certain foods in their raw forms, usually seeds from the bean family, are not nourishing to insects and animals even though there is no toxicity involved. Most famous in this regard is J. John Marshall, Ph.D., founder and past Editor-in-Chief of the Journal of Applied Biochemistry. It was Dr. Marshall who discovered that certain proteins found in beans block the enzyme alpha-amylase, which is necessary for the digestion of starches.
When we eat starches, a small amount of digestion takes place as we chew through the actions of the enzyme amylase, which is found in the saliva. However, starches and other carbohydrates are not exposed to the actions of this enzyme for any great period of time before they reach the stomach. Once in the stomach, food is bathed in hydrochloric acid, which makes up the bulk of the stomach's gastric secretions, and this acid inhibits starch digestion until food exits the stomach and enters the small intestine. Almost all complex carbohydrate digestion takes place in the duodenum, which is the section of the small intestine which adjoins the stomach. Here another key enzyme called alpha-amylase, joins with hydrochloric acid to breakdown the exceptionally long starch molecule into its component parts: first into sugars called dextrins, and then into glucose.
The starch blocker protein called phaseolamin, attaches to the carbohydrate molecule at precisely the point at which alpha-amylase normally would split the compound to yield dextrins. Result: the complex carbohydrate is not broken down into absorbable sugars and simply passes out of the body undigested.
The early clinical trials with phaseolamin sometimes yielded mixed results because commercial preparations of varying purity were used. Some of these preparations actually contained substantial amounts of amylase along with the amylase inhibitor! Early human trials with crude bean extracts also typically showed a problem with diarrhea. However, subsequent clinical investigations using highly purified materials demonstrated that phaseolamin, the active ingredient in starch blocker, at an effective dosage of level of approximately 2 - 3 grams does not cause diarrhea. Impurities found in crude extracts were at fault in most cases of gastrointestinal tract distress. Highly purified extracts have been found to be both safe and effective.
Researchers using human subjects have found that properly purified amylase inhibitors do, in fact, offer real benefits. In one study, it was found that use of the starch blocker reduced blood sugar levels and insulin levels following meals in both normal subjects and diabetics. In another study, it was found that appropriate doses of starch blocker can inhibit amylase activity in the small intestine on wheat starch (in this case, from spaghetti) by more than 96%. Yet a third study demonstrated that starch blocker not only improves insulin levels, reduces starch digestion, and reduces the release of sugar into the blood, but also may slow the emptying of the stomach. This means that starch blocker may help to reduce the return of hunger after meals, an especially pressing problem when individuals diet by simply reducing calories.
But, Does It Work for Dieters?
In his book, Have Your Bread and Eat It, John Marshall, the inventor of starch blocker, describes trials in which dieters tried reduced calorie diets with and without starch blocker, and further trials in which various amounts of starch were added back into the diet to determine the effects. In these trials, the starch blocker group typically lost twice as many pounds as did the control group. When calories were restricted, the starch blocker group also felt much less deprived.
The bottom line is that the new starch blocker seems to allow the possibility of eating a range of foods in satisfying amounts. Dieters do not have to feel deprived. Moreover, starch blocker may help to even out the ups and downs of the blood sugar blues. These benefits are not so small, when you think about it.
Phaseolaminä-is a trademark of Pharmachem Labs
About the author: Dr. Clouatre received both his M.A. and Ph.D. from the University of California, Berkeley where he also served as guest lecturer. He has authored several books and numerous articles including titles on Nutritional Supplements, Diet and Health. He has acted as advisor and consultant to some of the world's leading suppliers of health products.
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